Research Article

Nanoprodrugs of NSAIDs Inhibit the Growth of U87-MG Glioma Cells

Table 1

Size and polydispersity index (P.I.) of the nanoprodrugs ( š‘› = 3 , ± S . D . ) .

NSAIDs derivatives Size (nm)P.I.

ALA-TEG-Ind149 ± 1 (253 ± 25)*0.12 ± 0.02
ALA-TEG-Ibu149 ± 15 (251 ± 13)*0.09 ± 0.04
ALA-TEG-Npx147 ± 6 (298 ± 6)*0.11 ± 0.02
Ind2TEG140 ± 8 (159 ± 10)*0.11 ± 0.04
Ibu2TEG141 ± 11 (186 ± 11)*0.10 ± 0.02
Npx2TEG148 ± 1 (259 ± 9)*0.06 ± 0.02

āˆ— S ize of the nanoprodrugs in the absence of š›¼ -tocopherol [38]. ALA: š›¼ -lipoic acid; Ind: indomethacin; Ibu: ibuprofen; Npx: naproxen; TEG: tetraethylene glycol.