Research Article

Synthesis, and Characterization, and Evaluation of Cellular Effects of the FOL-PEG-g-PEI-GAL Nanoparticles as a Potential Non-Viral Vector for Gene Delivery

Table 1

The zeta potential and molecular weight of PEI, PEG-g-PEI copolymer, FOL-PEG-g-PEI copolymer, and FOL-PEG-g-PEI-GAL copolymer.

PolymerZeta potential of copolymer ( m V ) a Molecular weight of copolymer ( K D ) b Poly dispersity b

Polyethylenimine+ 4 1 . 1 ± 1 . 4 25.01.2
PEG-g-PEI+ 3 2 . 7 ± 3 . 2 26.91.3
FOL-PEG-g-PEI+ 2 1 . 7 ± 1 . 9 27.31.3
FOL-PEG-g-PEI-GAL+ 1 7 . 8 ± 1 . 5 27.61.3

a D e t e r m i n e d by 1H-NMR
b D e t e r m i n e d by GPC.