In Vitro and In Vivo Evaluation of Sol-Gel Derived TiO2 Coatings Based on a Variety of Precursors and Synthesis Conditions
Figure 4
Hematoxylin and eosin-stained specimens ((a), (c), (f), and (g)) and SEM microphotographs ((d), (h)) illustrating the stainless steel (a) and titanium (e) implantsurrounded by the bone tissue. Inflammatory and fibroblastic response around the implanted stainless steel material characterized by leukocyte and macrophages infiltration ((b), (c); arrow). SEM picture revealed only the local bone attachment to the austenitic steel implant ((d); arrow). In the group where titania dioxide material was applied a decrease in the inflammatory response within the tissue surrounding the implant was detected ((f), (g); arrow). Extensive bone formation ((e); arrow) with slight degree of osteolysis and granulocyte infiltration ((g), arrow) was noticed. SEM technique indicated a significant bone attachment to the titania dioxide biomaterial ((h), arrow). Mag. 300, 1000x for control and experimental materials, respectively; scale bar: 200 μm.
