PAMAM Dendrimers as Potential Carriers of Gadolinium Complexes of Iminodiacetic Acid Derivatives for Magnetic Resonance Imaging

Table 3

Biodistribution of four compounds (K1–K4) examined intravitally in rats.

SE T1	Imaging enhancement, the whole body		Imaging; enhancement, liver		Imaging; enhancement, kidneys		Imaging; enhancement, brain		Imaging; enhancement, testes
	%	% share	%	% share	%	% share	%	% share	%	% share
K1	24	100	116	24	107	3	6	0.15	16	0.4
K2	17	100	76	22	99	8	12	0.4	16	0.6
K3	20	100	59	15	136	5	13	0.4	21	0.6
K4	15	100	59	20	68	3	2	0.08	35	1.4

% share, percentage of gadolinium dose administered to animal.