Optimization and Characterization of Artesunate-Loaded Chitosan-Decorated Poly(D,L-lactide-co-glycolide) Acid Nanoparticles

Figure 1

4D response surface graphs of size in various conditions: at temperature = 25°C (a), at pH of CS solution = 4 (b), and at CS/PLGA mass ratio = 0.6 (c) and of zeta potential of ART/PLGA-CS NPs at pH of CS solution = 4 (d).

(a)

(b)

(c)

(d)