Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy

<div>Analysis of VEGF mRNA suppression using RT-PCR. Images of agarose gel electrophoresis 1% show the bands of GAPDH (housekeeping gene) (a) and VEGF (b). The graph represents relative mRNA expression in DLD-1 cells after treatment with different samples (c). SEM images of collagen layer (d) and MCLs at different magnifications (1000x (d), 15000x (e), and 20000x (f)).</div>

Journal of Nanomaterials

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Figure 9

Figure 9: Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy

Figure 9 | Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy 