Research Article

An Innovative Cell Microincubator for Drug Discovery Based on 3D Silicon Structures

Figure 10

Envelopes of the interferometric signal obtained using Hilbert transform. The signal obtained in position 4 is typical of an empty gap situation, where only air is inside the gap, without cell inside the gap and without cell on top of walls. The signal obtained in position 7 is relative to a situation where a cell is found inside the gap, attached to the vertical silicon wall, similarly to what is reported in the SEM photos in Figure 1(b). Inset: zoom to highlight the shift of the third peak only due to the presence of a cell in the gap in that horizontal position. In presence of a cell in the gap, adherent to the vertical wall, the measured optical path-length of the gap is greater than that obtained for an empty gap.