An Innovative Cell Microincubator for Drug Discovery Based on 3D Silicon Structures

Figure 7

Fluorescence microscopy images relative to HT1080 cells grown for 48 h on the 3D-SMS (walls horizontally oriented). Cells are here treated with Bleomycin. Images show a dramatic change in both density and morphology. The drug effect reached the deepest regions of the gaps of the SMS and induced cell detachment. A few cells, which survived on the top of the walls, show typical apoptotic characteristics. (a, b) 20x; (c, d) 40x.

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