Preparation and Evaluation of Doxorubicin-Loaded Micelles Based on Glycyrrhetinic Acid Modified Gelatin Conjugates for Targeting Hepatocellular Carcinoma

Figure 9

Fluorescence imaging of mice administrated with DiR-labeled GA-GEL-2 micelles. (a) Time-dependent in vivo images of mice bearing HCC tumors after i.v. injection. (b) Ex vivo NIR fluorescence image of dissected organs after 1, 12, and 24 h after injection. (A), heart; (B), liver and tumor; (C), spleen; (D), lung; and (E), kidney. (c) Fluorescence intensities of orthotopic tumors and dissected organs after 1 h after injection.

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