A pH-Responsive Multifunctional Nanocarrier in the Application of Chemo-Photodynamic Therapy

Figure 5

HEP2 cells stained by DAPI and observed by fluorescence microscopy after the cells were cocultured with RBITC-labeled nanoparticles for different coculture time (d, f, g, and h) and different nanoparticle concentrations (a, b, c, d, and e). In detail, cocultured with (a) 0 mg/mL nanoparticle for 24 h, (b) 0.1 mg/mL nanoparticle for 24 h, (c) 0.25 mg/mL nanoparticle for 24 h, (d) 0.5 mg/mL nanoparticle for 24 h, (e) 1 mg/mL nanoparticle for 24 h, (f) 0. 5 mg/mL nanoparticle for 2 h, (g) 0. 5 mg/mL nanoparticle for 6 h, and (h) 0. 5 mg/mL nanoparticle for 12 h.

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