Size-Dependent Cytotoxicity and Genotoxicity of Silver Nanoparticles in Cochlear Cells In Vitro

Table 2

The treatment of HaCaT and HEI-OC1 cells with AgNPs of four sizes resulted in intracellular concentrations of atomic silver proportional with the NP sizes (after 24 h incubation).

	Intracellular Ag concentration (μg/million cells)
AgNP size	HaCaT	HEI-OC1
5 nm	0.30 ± 0.05	0.29 ± 0.04
25 nm	0.40 ± 0.04	0.65 ± 0.03
50 nm	0.43 ± 1.1	0.78 ± 0.08
110 nm	1.1 ± 0.8	1.15 ± 0.7