Sequential Delivery of BMP2-Derived Peptide P24 by Thiolated Chitosan/Calcium Carbonate Composite Microspheres Scaffolds for Bone Regeneration

Figure 4

Histology of the cranial specimens at 4 and 8 weeks after implantation in vivo. (a) Hematoxylin and eosin staining of harvested tissues in Control, TCS/CA, TCS-5%P24/CA, and TCS-10%P24/CA groups. Yellow arrow represents new bone. (b) Masson’s trichrome staining of harvested tissues in Control, TCS/CA, TCS-5%P24/CA, and TCS-10%P24/CA groups. Black arrow represents new vessel.

(a)

(b)