Hollow Gold Nanoparticles Loaded with L-Buthionine-Sulfoximine as a Novel Nanomedicine for In Vitro Cancer Cell Therapy

<div>BSO@HAuNS induce cell death in mitochondrial-dependent pathway. A549 cells were exposed to various treatments for 72 h, then harvested, and washed twice with PBS. (a) After treatment, the cells were processed by JC-1 staining and measured by flow cytometry. Mitochondrial membrane potential changes were quantified by fluorescence shift (red to green) of samples. (b) Following exposure to BSO, PEG-SH-HAuNS, and BSO@HAuNS, the Fluo-4-dependent fluorescence of the different samples was indicated by flow cytometry. Numbers depict the effect of BSO@HAuNS on A549 cytosolic Ca<sup>2+</sup> concentration. 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Journal of Nanomaterials

fig6

Figure 6

Figure 6: Hollow Gold Nanoparticles Loaded with L-Buthionine-Sulfoximine as a Novel Nanomedicine for In Vitro Cancer Cell Therapy 