Synthesis of Cellulose Nanocrystals (CNCs) from Brewer’s Spent Grain Using Acid Hydrolysis: Characterization and Optimization

Table 2

RSM-CCD experimental design matrix and response data.

Std	Run	Time (min)	Temperature (°C)	Sulfuric acid (wt%)	Liquid-solid ratio (ml/g)	Yield (%)
21	1	40	50	47	20	41.61
19	2	40	45	51	20	41.77
11	3	35	55	47	25	37.89
14	4	45	45	55	25	36.78
9	5	35	45	47	25	36.18
4	6	45	55	47	15	37.83
2	7	45	45	47	15	35.31
25	8	40	50	51	20	43.02
13	9	35	45	55	25	38.34
12	10	45	55	47	25	38.51
24	11	40	50	51	25	42.79
10	12	45	45	47	25	36.91
22	13	40	50	55	20	42.33
8	14	45	55	55	15	36.96
3	15	35	55	47	15	35.73
5	16	35	45	55	15	36.61
7	17	35	55	55	15	36.74
26	18	40	50	51	20	42.95
16	19	45	55	55	25	37.74
18	20	45	50	51	20	41.55
17	21	35	50	51	20	41.14
20	22	40	55	51	20	42.46
6	23	45	45	55	15	37.42
15	24	35	55	55	25	37.58
1	25	35	45	47	15	34.42
23	26	40	50	51	15	42.46