Ultrasensitive Detection of Lysozyme upon Conformational Change of DNA Duplex

Figure 4

Colorimetric nanoaptasensor for analysis of lysozyme based on the electrostatic interaction of ssDNA-AuNPs and dsDNA-AuNPs. (a) The color response of dsDNA-AuNPs as a function of lysozyme concentration after salt addition; (b) UV–Vis absorption spectra of dsDNA-AuNPs in the presence of various concentration of lysozyme from 0.01 to 500 pM.

(a)

(b)