Magnesium–Magnetic Field Synergy Enhances Mouse Bone Marrow Mesenchymal Stem Cell Differentiation into Osteoblasts Via the MAGT1 Channel

Figure 1

Study design. (a) BMSCs were divided into four groups: control, Mg²⁺, SMF, and Mg²⁺-SMF. This grouping was done to compare the differences between the magnetic field intervention alone, the magnesium ion intervention and the synergistic intervention. (b) SiRNA transfection was used to silence genes in the following groups: non-specific control (nc), siRNA (si), Mg²⁺-SMF non-specific control (ms + nc), and Mg²⁺-SMF siRNA (ms + si). nc and si to verify whether siRNA reagents are toxic to cells, ms + nc and ms + si to verify the role of target genes in synergistic osteogenesis.