A Novel Nanomedicine System TAR-AuNSs/Dox for the Treatment of Drug-Resistant Lymphoma

Figure 7

The killing effect of TAR-AuNSs/Dox on drug-resistant tumor-bearing mice. Body weights (a), tumor images (b), tumor volumes (c), and tumor weights (d) of mice with PBS, Dox, AuNSs/Dox, and TAR-AuNSs/Dox, respectively. (e) Fluorescence images of cryosectioned tumors after application of Dox, AuNSs/Dox, and TAR-AuNSs/Dox at 48 h. Blue represents nuclei; red represents Dox. The expression of P-gp in drug-resistant tumor was detected by western blot (f) and immunohistochemical staining (g) after application of Dox, AuNSs/Dox, and TAR-AuNSs/Dox. P-gp-positive cells are stained in brown. .

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