Calcium Phosphorus Nanoparticles Coloaded with Paclitaxel and ADAM-10-siRNA for the Treatment of Triple Negative Breast Cancer

Figure 1

Preparation and characterization of CaP-PTX/siADAM10 NPs with core-shell-distinct structure. (a) Schematic route of CaP-PTX/siADAM10 NPs. The diameter (b) and zeta potential (c) detection of CaP-PTX/siADAM10 NPs. (d) TEM image of PTX/siADAM10 NPs-ICAM. Scale bar, 100 nm. (e) Binding assay for CaP-PTX/siADAM10 NP target detection. (f) Stability analysis of CaP-PTX/siADAM10 NPs at 4, 25, and 37°C. (g) Release profile analysis of PTX and siRNA at pH 7.4, 6.0, and 5.0. Data as .

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