Calotropis gigantea Assisted Synthesis of Zinc Oxide Nanoparticle Catalysis: Synthesis of Novel 3-Amino Thymoquinone Connected 1,4-Dihyropyridine Derivatives and Their Cytotoxic Activity

Table 3

In vitro cytotoxicity of synthesized derivatives (1a-1j) on normal cells^a.

Compounds	MRC5	HEK-293	LO2
	IC50 (μm)	IC50 (μm)	IC50 (μm)
1a	56.36	69.06	67.48
1b	77.21	62.12	70.17
1c	76.66	51.14	79.10
1d	58.25	76.14	66.24
1e	70.76	57.09	56.01
1f	89.24	88.17	80.24
1g	59.61	66.24	68.54
1h	66.32	67.01	58.22
1i	74.41	75.44	65.70
1j	71.14	52.71	70.12

^aEach compound was tested in triplicate. All error bars represent from three independent experiments.