Research Article
Functional Nanorealgar Quantum Dots with Aggregation-Induced Emission Enhancement for Tumor Neovascular-Targeted Theranostics
Figure 5
(a) In vivo fluorescence imaging (Ex = 570 nm, Em = 660 nm) of tumor-bearing mice after intravenous injection of NR@RGD QDs (1 mg As·kg‒1 body weight); (b) corresponding fluorescence CI changes at the tumor sites and adjacent muscle tissue at different times; (c) ex vivo fluorescence images of major normal organs (heart, liver, spleen, lung, and kidneys) and tumor tissues after injection of NR@RGD QDs collected at 4 and 24 hr; (d) CLSM images for tumor vascularization after treatment with NR@RGD QDs; (e) schematic illustration of NR@RGD QDs-mediated tumor vascular targeting therapy.
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