Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Postoperative Muscle and Substrate Metabolism
Table 3
Plasma glucose, urea and CRP levels pre- and postoperatively.
D0
D1
D2
D3
Glucose (mmol/L)
Control
4.9 (4.3–5.4)
8.2 (6.2–9.8)*
6.6 (5.6–7.2)
5.8 (5.3–6.5)
GH
4.6 (3.9–5.2)
8.2 (6.8–11.1)*
8.2 (6.7–10.9)*
9.1 (7.0–11.2)*#
GH-IGF-1
4.8 (4.7–5.2)
8.7 (7.3–8.9) **
7.4 (6.5–9.9) **
7.4 (6.9–12.6) **#
Urea (mmol/L)
Control
4.0 (3.1–5.2)
4.4 (3.1–5.3)
3.4 (3.1–3.5)
3.4 (3.2–4.1)
GH
4.0 (3.1–6.3)
3.1 (2.9–5.8)
2.3 (1.9–3.5)*
2.0 (1.4–2.9)*#
GH-IGF-1
4.1 (3.5–4.9)
4.4 (3.5–4.9)
2.5 (2.0–2.9)*
1.9 (1.4–2.2) **#
CRP (mg/L)
Control
7 (5–13)
59 (55–91) **
104 (94–130) **
67 (59–109) **
GH
5 (5–14)
46 (39–102)*
106 (43–145)*
69 (29–88)*
GH-IGF-1
12 (5–20)
82 (66–86) **
135 (82–155) **
91 (53–114) **
*and **indicate a postoperative difference within the groups ( and ) as compared to D0, and # indicates a difference between the controls and the groups given growth factors (). Values are given as medians and quartiles.
