Research Article
Association of Apolipoprotein E Gene Polymorphism with Lipid Profile and Ischemic Stroke Risk in Type 2 Diabetes Mellitus Patients
Table 1
Demographic, clinical, and biochemical data of the participants.
| | Variable | T2DM + IS (n = 30) | T2DM (n = 30) | |
| | Age (years) | 57.3 ± 9.63 | 57.47 ± 9.31 | 0.946 | | Sex (male/female) | 17/13 | 18/12 | 0.793 | | BMI (kg/m2) | 25.43 (22.96–27.47) | 25.58 (23.73–28.12) | 0.344 | | SBP (mmHg) | 144 ± 24.86 | 125.67 ± 15.69 | 0.001 | | DBP (mmHg) | 90 (80–100) | 80 (70–80) | 0.001 | | Hypertension | 20 (66.7%) | 8 (26.7%) | 0.002 | | Diabetes duration (years) | 4 [2–6] | 3 [2–5] | 0.688 | | Smoking | 17 (56.7%) | 7 (23.3%) | 0.008 | | Dyslipidemia | 25 (83.3%) | 22 (73.3%) | 0.347 | | FPG (mg/dL) | 157.23 ± 53.59 | 160 ± 46.85 | 0.832 | | 2-hour plasma glucose (mg/dL) | 167.07 ± 52.24 | 224.33 ± 60.14 | <0.001 | | HbA1C (mg/dL) | 7.2 (6.5–9.2) | 7.55 (6.8–8.8) | 0.583 | | TC (mg/dL) | 201.5 (172–252) | 174.5 (144–202) | 0.027 | | TG (mg/dL) | 113 (101–167) | 128.5 (95–194) | 0.912 | | LDL-C (mg/dL) | 143 (120–189) | 116 (91–143) | 0.005 | | HDL-C (mg/dL) | 41.17 ± 12 | 42.77 ± 12.54 | 0.616 |
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BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, FPG: fasting plasma glucose, HbA1C: hemoglobin A1C, TC: total cholesterol, TG: triglycerides, LDL-C: low-density lipoprotein cholesterol, HDL-C: high-density lipoprotein cholesterol. Statistically significant difference in comparison between two groups ( ). |
