Research Article
Association of Apolipoprotein E Gene Polymorphism with Lipid Profile and Ischemic Stroke Risk in Type 2 Diabetes Mellitus Patients
Table 3
Association of apolipoprotein E gene polymorphism with lipid levels and other metabolic-vascular risk factors.
| | Variables | ε2 carriers | ε3 homozygotes | ε4 carriers | |
| | Lipid profile | | TC (mg/dL) | 175 (135.5–210.5) | 202 (172.5–246.5) | 175.5 (155–228) | 0.423 | | TG (mg/dL) | 158 (102–356.5) | 115 (93–172.5) | 130 (100–185) | 0.439 | | LDL-C (mg/dL) | 101.5 (79–146.5) | 143 (119–171) | 120 (109–161) | 0.152 | | HDL-C (mg/dL) | 33.25 ± 10.11a | 47.37 ± 11.24 | 39.41 ± 12.08b | 0.005 |
| | Metabolic-vascular risk factors | | Age (years) | 58.13 ± 13.41 | 56 ± 8.87 | 58.05 ± 8.61 | 0.715 | | BMI (kg/m2) | 26.38 ± 3.21 | 25.65 ± 2.96 | 26.39 ± 3.14 | 0.668 | | Diabetes duration (years) | 6 ± 4.81 | 3.91 ± 3.56 | 3.5 ± 2.38 | 0.200 | | Sex (male/female) | 5/3 | 13/14 | 14/8 | 0.548 | | Hypertension (%) | 37.5 | 51.9 | 45.5 | 0.818 | | Dyslipidemia (%) | 87.5 | 77.8 | 77.3 | 1.000 |
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Statistically significant difference in comparison between three groups ( ). a for ε2 carriers vs. ε3 homozygotes. b for ε4 carriers vs. ε3 homozygotes. |
