Research Article

Association of Apolipoprotein E Gene Polymorphism with Lipid Profile and Ischemic Stroke Risk in Type 2 Diabetes Mellitus Patients

Table 4

Bivariate analysis of variables related to ischemic stroke in T2DM.

VariablesT2DM + IS (n = 30) (%)T2DM (n = 30) (%)OR (95% CI)

Hypertension
 Yes20 (71.4)8 (28.6)5.5 (1.81–16.68)0.002
 No10 (31.3)22 (68.8)

Smoking habits
 Yes17 (70.8)7 (29.2)4.3 (1.41–13.07)0.008
 No13 (36.1)23 (63.9)

2-hour plasma glucose
 High21 (42.9)28 (57.1)0.17 (0.03–0.85)0.020
 Normal9 (81.8)2 (18.2)

TC
 High16 (66.7)8 (33.3)3.14 (1.07–9.27)0.035
 Normal14 (38.9)22 (61.1)

LDL-C
 High19 (65.5)10 (34.5)3.46 (1.19–9.99)0.020
 Normal11 (35.5)20 (64.5)

ε4 vs. ε3 carriers
ε4 carriers14 (63.6)8 (36.4)2.19 (0.69–6.93)0.181
ε3 homozygotes12 (44.4)15 (55.6)

Statistically significant difference ().