Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurChexia)

Table 3

Secondary outcomes: handgrip strength, body mass index, and absolute lymphocyte count among the curcumin and placebo group patients, as an average change and percentage of an average change.

Group

Handgrip strength, kg (mean ± SD)

Body mass index (mean ± SD)

Absolute lymphocyte count, cell/mm^3 (mean ± SD)

Week 0

Week 8

Mean change (95% CI)

% Change (95% CI)

Week 0

Week 8

Mean change (95% CI)

% Change (95% CI)

Week 0

Week 8

Mean change (95% CI)

% Change (95% CI)

Curcumin

26.24 ± 4.69

26.85 ± 6.18

0.61 (−2.17, 3.39)

2.73 (−9.62, 15.07)

18.49 ± 2.2

18.38 ± 2.47

−0.1 (−0.71, 0.51)

−0.63 (−4.1, 2.84)

1017.6 ± 693.4

789.9 ± 547.61

−227.7 (−694.7, 239.3)

−4.55 (−45.78, 36.69)

Placebo

26.19 ± 8.48

25.57 ± 8.24

−0.62 (−3.03, 1.79)

−0.82 (−10.16, 8.52)

19.53 ± 2.86

18.65 ± 2.47

−0.88 (−1.85, 0.08)

−4.2 (−8.64, 0.25)

1495 ± 756.88

606.1 ± 191.89

−888.9 (−1439.45, −338.35)

−48.31 (−68.62, −28)

values

0.956

0.935

0.206

0.344

0.053

0.05