Research Article

Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized Controlled Trial

Table 1

Baseline characteristics of participants among the study groups.

VariableCurcumin (n = 26)Vitamin E (n = 27)Placebo (n = 28) value

Age (year)52.0 (2.5)52.5 (3.2)52.1 (2.7)0.764
Menopause age (year)49.3 (2.2)49.6 (2.8)48.6 (3.5)0.358
Childbirth2.5 (1.0)2.8 (0.9)2.6 (1.0)0.646
Family members1.6 (0.5)1.5 (0.6)1.4 (0.5)0.235
Weight (kg)72.3 (8.8)71.8 (10.9)74.0 (10.4)0.710
BMI (kg/m2)30.5 (4.6)29.9 (4.4)30.1 (3.7)0.880
Age (year)52.0 (2.5)52.5 (3.2)52.1 (2.7)0.764
Total physical activity (MET‑min.week)±396.6 (336.6–815.5)442.0 (326.5–1026.5)386.5 (340.5–864.5)0.588
Marriage statusSingle and widow5 (17.9)3 (10.7)3 (10.7)
Married23 (82.1)25 (89.3)25 (89.3)
Educational levelIlliterate and primary13 (46.4)13 (46.4)13 (46.4)
Secondary and high school6 (21.4)11 (39.3)8 (28.6)
Diploma and more9 (32.1)4 (14.3)7 (25.0)
OccupationHousewife27 (96.4)26 (92.9)28 (100.0)
Occupied andretired1 (3.6)2 (7.1)0 (0.0)
Husband educationIlliterate andprimary2 (7.4)8 (28.6)8 (28.6)
Secondary andhigh school12 (44.4)10 (39.3)7 (25.0)
Diploma andmore14 (50.0)9 (33.3)13 (46.4)
Husband occupationSelf-occupied8 (29.6)13 (46.4)16 (57.1)
Employee5 (17.9)3 (10.7)4 (14.3)
Retired13 (46.4)10 (37.0)7 (25.0)
Worker2 (7.1)2 (7.1)1 (3.6)
Family incomeSufficient13 (46.4)11 (40.7)15 (53.6)
Less than sufficient15 (53.6)16 (59.3)13 (46.4)
Life satisfactionYes26 (92.9)24 (92.3)22 (84.6)
No2 (7.1)2 (7.7)4 (15.4)
Smoker husbandYes7 (25.0)7 (25.0)8 (28.6)
No21 (75.5)21 (75.5)20 (71.4)
Living with husband familyYes1 (3.6)0 (0.0)1 (3.6)
No27 (96.4)28 (100.0)27 (96.4)

BMI: body mass index, mean (SD), ±median (p25–p75), number (percent); one-way ANOVA, chi-square, linear by linear chi-square, Kruskal-Wallis.