Research Article

Examining the Effect of Consuming C8 Medium-Chain Triglyceride Oil for 14 Days on Markers of NLRP3 Activation in Healthy Humans

Table 2

Acetylation of lysine residues 9 and 14 on monocyte histone H3.

Estimated marginal means (95% CI) value from linear mixed effects model
PrePostMain effect of supplementation

Acetylated histone H3 lysine 9 (% positive)12.6 (7.4, 21.3)8.9 (5.3, 15.1)0.201
Acetylated histone H3 lysine 9 (MFI; a.u.)4.3 (3.7, 5)4.5 (3.8, 5.1)0.247
Acetylation histone H3 lysine 14 (% positive)1.2 (0.3, 4.4)1.3 (0.4, 4.7)0.677
Acetylated histone H3 lysine 14 (MFI; a.u.)2.4 (2.1, 2.6)2.2 (1.9, 2.4)0.039

Data are estimated marginal means with 95% confidence intervals, and values obtained from a linear mixed effects model. MFI, median fluorescence intensity. N = 12; N = 11.