Examining the Effect of Consuming C8 Medium-Chain Triglyceride Oil for 14 Days on Markers of NLRP3 Activation in Healthy Humans
Table 2
Acetylation of lysine residues 9 and 14 on monocyte histone H3.
Estimated marginal means (95% CI)
value from linear mixed effects model
Pre
Post
Main effect of supplementation
Acetylated histone H3 lysine 9 (% positive)
12.6 (7.4, 21.3)
8.9 (5.3, 15.1)
0.201
Acetylated histone H3 lysine 9 (MFI; a.u.)†
4.3 (3.7, 5)
4.5 (3.8, 5.1)
0.247
Acetylation histone H3 lysine 14 (% positive)
1.2 (0.3, 4.4)
1.3 (0.4, 4.7)
0.677
Acetylated histone H3 lysine 14 (MFI; a.u.)
2.4 (2.1, 2.6)
2.2 (1.9, 2.4)
0.039
Data are estimated marginal means with 95% confidence intervals, and values obtained from a linear mixed effects model. MFI, median fluorescence intensity. N = 12; †N = 11.