Research Article

Enteral Nutrition Safety and Outcomes of Patients with COVID-19 on Continuous Infusion of Neuromuscular Blockers: A Retrospective Study

Table 1

Baseline characteristics of the study patients.

Nonproned N = 66Proned N = 115 value

Age (yrs), mean ± SD62.0 ± 12.860.9 ± 14.10.62
Male gender, N (%)51 (78.46%)77 (66.97%)0.10
BMI (kg/m2), median (Q1, Q3)32.8 (28.8, 39.8)30.2 (25.7, 36.3)0.01

Comorbidities, N (%)
Diabetes49 (74.2%)80 (69.6%)0.50
Hypertension44 (66.7%)74 (64.3%)0.75
Stroke4 (6.1%)6 (5.2%)1.0
Liver disease1 (1.5%)1 (0.9%)1.0
Asthma5 (7.6%)8 (7%)1.0
Cancer5 (7.6%)4 (3.5%)0.29
Heart failure7 (10.6%)8 (7%)0.39
Chronic kidney disease10 (15.2%)11 (9.6%)0.26

Pertinent laboratory findings on the day of admission to ICU
White blood cells × (109/L), mean ± SD11.9 ± 6.210.0 ± 5.50.05
Lymphocyte count × (109/L), mean ± SD0.8 (0.5, 1.3)0.9 (0.6, 1.2)0.93
Neutrophil count × (109/L), mean ± SD8.8 ± 4.27.6 ± 3.80.20
Hemoglobin (g/L), median (Q1, Q3)122 (110, 135)129 (119, 141)0.04
Platelet × (109/L), mean ± SD275.2 ± 130.0249.5 ± 93.30.18
Creatinine (μmol/L), median (Q1, Q3)105 (73, 162)93 (72, 138)0.19
Lactate (mmol/L), median (Q1, Q3)1.85 (1.35, 2.66)1.72 (1.15, 2.53)0.28
Lactate dehydrogenase (U/L), median (Q1, Q3)604 (476, 809)643 (508, 824)0.51
Ferritin (μg/mL), median (Q1, Q3)824 (463, 2067)808 (505, 2097)0.88
Fibrinogen (g/L), mean ± SD5.6 ± 1.85.7 ± 1.60.74
D-dimer (μg/mL), median (Q1, Q3)1.8 (0.8, 4.0)1.1 (0.7, 3.2)0.21
C-reactive protein (mg/L), mean ± SD160.4 ± 82.0174.0 ± 111.80.77

Medications
Corticosteroids, N (%)48 (72.7%)91 (79.1%)0.33

BMI: body mass index, ICU: intensive care unit, Q1: first quartile, Q3: third quartile, and SD: standard deviation. Continuous variables with normal distribution are presented as mean with standard deviation and are compared using the independent t-test (significant at <0.05). Continuous variables with normal distribution are presented as median with the first and third quartile and are compared using Mann–Whitney test (significant at <0.05).