Research Article

Associations of Plasma BDNF and BDNF Gene Polymorphism with Cardiometabolic Parameters in Thai Children: A Pilot Study

Table 4

Genotypic and allelic distribution of the single nucleotide polymorphisms BDNF G196A and C270T in nonobese and obese children.

ObeseNonobeseGenotypic or allelic
N (%)N (%) value

BDNF G196A
AA40 (21.0)61 (21.9)
AG82 (43.2)137 (49.1)0.284
GG68 (35.8)81 (29.0)
GG vs. GA + AAa0.721 (0.486–1.070)Reference
[0.104]
A allele0.43 (162)0.46 (259)0.252
G allele0.57 (218)0.54 (299)

BDNF C270T
TT2 (1.1)3 (1.1)
TC43 (22.6)55 (19.7)0.747
CC145 (76.3)221 (79.2)
CC vs. CT + TTa1.183 (0.769–1.840)Reference
[0.457]
T allele0.12 (47)0.11 (61)0.499
C allele0.88 (333)0.89 (497)

aValues are the odds ratio with 95% confidence interval in parentheses; values are in brackets.