Research Article
Associations of Plasma BDNF and BDNF Gene Polymorphism with Cardiometabolic Parameters in Thai Children: A Pilot Study
Table 4
Genotypic and allelic distribution of the single nucleotide polymorphisms BDNF G196A and C270T in nonobese and obese children.
| | Obese | Nonobese | Genotypic or allelic | N (%) | N (%) | value |
| BDNF G196A | AA | 40 (21.0) | 61 (21.9) | | AG | 82 (43.2) | 137 (49.1) | 0.284 | GG | 68 (35.8) | 81 (29.0) | | GG vs. GA + AAa | 0.721 (0.486–1.070) | Reference | | | [0.104] | | | A allele | 0.43 (162) | 0.46 (259) | 0.252 | G allele | 0.57 (218) | 0.54 (299) | |
| BDNF C270T | TT | 2 (1.1) | 3 (1.1) | | TC | 43 (22.6) | 55 (19.7) | 0.747 | CC | 145 (76.3) | 221 (79.2) | | CC vs. CT + TTa | 1.183 (0.769–1.840) | Reference | | | [0.457] | | | T allele | 0.12 (47) | 0.11 (61) | 0.499 | C allele | 0.88 (333) | 0.89 (497) | |
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aValues are the odds ratio with 95% confidence interval in parentheses; values are in brackets. |