Increasing Possibilities of Nanosuspension

Table 2

Summary of drug nanosuspensions.

Drug	Drug delivery route	Manufacturing method	Indication
Silybin	Oral, IV	HPH	Human prostate cancer [37, 38]
All-trans retinoic acid (ATRA)	IV, oral, and skin	Modified precipitation method	Antiproliferative drug against tumor [14, 39]
Mitotane	Oral	Emulsion as template	Symptomatic treatment of advanced adrenocortical carcinoma (ACC) [38, 40, 41]
Clofazimine	Intravenous	High-pressure homogenization	Murine Mycobacterium avium infection [42]
Cyclosporin A	Inhalation	Antisolvent precipitation	In immunosuppression [43, 44]
Amphotericin B	Ocular	Solvent displacement process	Management of ophthalmic fungal infections [45]
Olmesartan medoxomil	Oral	Media milling	Antihypertensive agent [46]
Simvastatin	Oral	Nanoprecipitation	Lipid-lowering agent [47]
Azithromycin	Oral	HPH	Antimicrobial [38, 41]
Nifedipine	Oral	Dry cogrinding	Treatment of vascular diseases [48–50]
Salbutamol sulfate	Pulmonary inhalation.	HPH	Antiasthmatic [51]
Diclofenac	Transdermal	Emulsification	NSAID [52]
Oridonin	IV	HPH	Antitumor [53, 54]
Albendazole	Oral	HPH	Lipophilic anthelmintic drug [55]
Loviride	IV	Milling	Antivirotic [56, 57]
Naproxen	I.P	Precipitation	Analgesic activity [58]
Paclitaxel	IV	HPH	Anticancer [8, 36]
Nevirapine	Parenteral	HPH	Antiretroviral [57]
Ibuprofen	Ocular	Emulsion solvent diffusion method	Ocular anti-inflammatory activity [6, 59]
Megestrol acetate	Oral	Laser fragmentation and media milling	Anorexia and cachexia [19, 60]