Research Article
Electrochemically Effective Surface Area of a Polyaniline Nanowire-Based Platinum Microelectrode and Development of an Electrochemical DNA Sensor
Figure 5
(a) EIS spectra (Nyquist plots) of the DNA sensors after hybridization with different concentrations of complementary target DNA: (a) 0 M, (b) 1.0 × 10−13 M, (c) 1.0 × 10−12 M, (d) 1.0 × 10−11 M, (e) 1.0 × 10−10 M, (f) 1.0 × 10−9 M, and (g) 1.0 × 10−8 M, respectively. Experimental conditions: EIS spectra were measured in PBS buffer (pH 7.4) solution consisting K3Fe(CN)6/K4Fe(CN)6 (0.005 M) and 0.1 M KCl, frequency range: 100 kHz–100 mHz, EAC = 5 mV, and EDC = 160 mV; and (b) response of the DNA sensors to (a) different concentrations of complementary target DNA and (b) 1.0 × 10−8 M of noncomplementary target DNA.
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