Journal of Oncology / 2008 / Article / Tab 1 / Research Article
Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival: Results from a Single Institutional Study Table 1 Patient and tumor characteristics (all
patients).
Parameter No. of patients (%) Sex Male 11 (35%) Female 20 (65%) Age (range) 56 (20–83) Race Caucasian 28 (90%) African American 3 (10%) History of tobacco use 11 (35%) Family history of malignancy 7 (23%) Breast cancer 4 (13%) Breast and ovarian cancers 2 (6%) Sarcoma 1 (3%) Prior cancer 4 (13%) Breast 1 (3%) Melanoma 1 (3%) Hodgkin’s disease 1 (3%) Prior radiation 3 (10%) TNM stage T2bN0M0 25 (81%) T2bN0M1 4 (13%) Desmoid 2 (6%) Grade 1 6 (19%) 2 6 (19%) 3 17 (55%) AJCC stage I 10 (32%) III 15 (48%) IV 4 (13%) Recurrent RPS 7 (23%) Pretreatment size of RPS (range) 10.5 cm (
) Histology Leiomyosarcoma 15 (48%) Liposarcoma 10 (32%) Myxoid 3 (10%) Dedifferentiated 4 (13%) Desmoid 2 (6%) Malignant fibrous histiocytoma 3 (10%) Inflammatory myofibroblastic sarcoma 1 (3%) CD 117 staining Not done 16 (52%) Negative 10 (32%) Positive 5 (16%) Imatinib mesylate given 1 (3%) Symptoms at presentation Pain/discomfort 20 (65%) Weight loss (range) 9 (31%) 10–30 lbs Early satiety/decreased appetite 6 (21%) Nausea 3 (10%) Change in menses 2 (7%) Small bowel obstruction 2 (7%)