Research Article

Toll-Like Receptor 7 Agonist Therapy with Imidazoquinoline Enhances Cancer Cell Death and Increases Lymphocytic Infiltration and Proinflammatory Cytokine Production in Established Tumors of a Renal Cell Carcinoma Mouse Model

Figure 2

Intratumoral 3M011 injection does not alter mouse weight. (a) Mean percent change in mouse weight following 3M011 versus placebo treatment on day 0 ( 𝑃 = 0 . 4 7 , 0.14, and 0.82 at 2, 4, and 7 days, resp.). (b) Mean percent change in mouse weight following 3M011 versus placebo treatment on day 7 ( 𝑃 = 0 . 1 3 ). Error bars = standard error of the mean.
103298.fig.002a
(a)
103298.fig.002b
(b)