Early Response to Dexamethasone as Prognostic Factor: Result from Indonesian Childhood WK-ALL Protocol in Yogyakarta

Table 3

Univariate and multivariate analyses of factors predicting disease-free survival.

Factors	HR	95% CI	𝑃 value
Univariate analyses
Age at diagnosis	2.64^1	1.32–5.26	0.006
WBC group at diagnosis	1.99^2	1.06–3.74	0.03
Early response to treatment	2.02^3	1.04–3.92	0.04
Gender	0.89^4	0.52–1.53	0.67
Multivariate analysis ^a
Age at diagnosis	2.63	1.32–5.26	0.006

^aFinal model. Age at diagnosis, WBC group, and early response were included as factors in a stepwise analysis. Note that all three were also factors to stratify patient into the HR group. The same model was found using forward selection.
¹For age <1 and ≥10 years relative to 1–9 years.
²For WBC ≥ 50,000 relative to WBC < 50,000.
³For poor responders relative to good responders.
⁴For girls relative to boys.