Antiproliferative and Apoptotic Effects of a Specific Antiprostate Stem Cell Single Chain Antibody on Human Prostate Cancer Cells
Figure 4
Percentages of cell growth of DU-145 and LNCaP cells after 24 h of treatment with scFv C5-I (a) and scFv C5-II (b). Treatment with scFv C5-I had no effect on the growth of the cancer cells (a). All concentrations of scFv C5-II (200, 500, and 1000 scFv/cell) significantly inhibited the cell growth of DU-145 cells with no effect on PSCA-negative LNCaP cells (*** <0.001).