Helicobacter pylori and Epstein–Barr Virus Infection in Gastric Diseases: Correlation with IL-10 and IL1RN Polymorphism
Table 5
Frequency of the polymorphisms IL1RN and IL-10 loci. Results of univariate and multivariate analysis among groups.
Parameters
Group NGM
Group GCA
Group KG
Group ML
Univariate and multivariate analysis
Polymorphism IL-1RN
1/1
50.00% (12/24)
62.50% (15/24)
41.67% (10/24)
70.83% (17/24)
0.179 (C)
1/2
29.17% (7/24)
25.00% (6/24)
33.33% (8/24)
0.00% (0/24)
0.0239 (C) group ML, (Z)
2/2
20.83% (5/24)
8.33% (2/24)
16.67% (4/24)
29.17% (7/24)
0.314 (C)
1/3
0.00% (0/24)
4.17% (1/24)
4.17% (1/24)
0.00% (0/24)
0.564 (C)
4/4
0.00% (0/24)
0.00% (0/24)
4.17% (1/24)
0.00% (0/24)
0.387 (C)
Polymorphism IL-10 (−1082)
AA
41.67% (10/24)
45.83% (11/24)
54.17% (13/24)
50.00% (12/24)
0.841 (C)
AG
33.33% (8/24)
33.33% (8/24)
29.17% (7/24)
20.83% (5/24)
0.875 (C)
GG
25.00% (6/24)
20.83% (5/24)
16.67% (4/24)
29.17% (7/24)
0.768 (C)
Significant test; significant most frequent; significant less frequent; # = no localized significant modality with significant level <0.05; C = multicomparison chi-square test; Z = Z-test; HP = H. pylori; NGM = normal gastric mucosa; GCA = active chronic gastritis; KG = gastric cancer; ML = MALT lymphoma; = value.
