Helicobacter pylori and Epstein–Barr Virus Infection in Gastric Diseases: Correlation with IL-10 and IL1RN Polymorphism

Table 6

Results of univariate and multivariate linear correlation analysis between polymorphism of vacA, IL-1RN and IL-10 with age, gender, H. pylori, EBV, coinfected, and gastric disease.

Linear correlation analysis	Univariate analysis	Multivariate analysis
	R ( value)	Multiple linear correlation coefficient = 0.149
Polymorphism IL-1RN/age	−0.092 (0.371)	Rpartial = −0.057; value = 0.593
Polymorphism IL-1RN/gender	−0.038 (0.716)	Rpartial = −0.013; value = 0.905
Polymorphism IL-1RN/H. pylori	0.02 (0.846)	Rpartial = −0.027; value = 0.800
Polymorphism IL-1RN/EBV	−0.027 (0.794)	Rpartial = 0.052; value = 0.622
Polymorphism IL-1RN/coinfected	−0.015 (0.886)	Rpartial = −0.011; value = 0.917
Polymorphism IL-1RN/gastric disease	−0.097 (0.348)	Rpartial = −0.107; value = 0.314
	R ( value)	Multiple linear correlation coefficient = 0.215
Polymorphism IL-10/age	0.116 (0.259)	Rpartial = 0.106; value = 0.316
Polymorphism IL-10/gender	−0.142 (0.167)	Rpartial = −0.125; value = 0.237
Polymorphism IL-10/H. pylori	0.102 (0.322)	Rpartial = −0.024; value = 0.821
Polymorphism IL-10/EBV	0.081 (0.430)	Rpartial = −0.054; value = 0.619
Polymorphism IL-10/coinfected	0.101 (0.329)	Rpartial = 0.062; value = 0.560
Polymorphism IL-10/gastric disease	0.061 (0.552)	Rpartial = 0.027; value = 0.797

Significant test; R = Pearson’s linear correlation coefficient; R_partial = the partial correlation coefficient is the coefficient of correlation of the variable with the dependent variable, adjusted for the effect of the other variables in the mode; coinfected = patients with H. pylori and EBV.