Altered CSF Proteomic Profiling of Paediatric Acute Lymphocytic Leukemia Patients with CNS Infiltration

Table 1

Statistically significant increased or decreased proteins in ALL samples during induction with P<0.05.

Protein	Gene name	Protein ID	Change trend	P value
complement C4A (Rodgers blood group)	C4A	P0C0L4	↑	0.011
Histidine rich glycoprotein	HRG	P04196	↑	0.016
apolipoprotein A1	APOA1	P02647	↑	0.025
kallikrein related peptidase 6	KLK6	Q92876	↑	0.025
carnosine dipeptidase 1	CNDP1	Q96KN2	↑	0.026
complement factor H	CFH	P08603	↑	0.029
alpha-2-macroglobulin	A2M	P01023	↑	0.05
apolipoprotein D	APOD	P05090	↓	0.018
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	WFIKKN2	Q8TEU8	↓	0.024
secreted protein acidic and cysteine rich	SPARC	P09486	↓	0.037