Research Article
Association of NEFL Gene Polymorphisms with Wilms’ Tumor Susceptibility in Chinese Children
Table 2
Stratification analysis of protective genotypes and Wilms' tumor susceptibility.
| | Variables | rs11994014 | Adjusted | | rs2979704 | Adjusted | | Combined genotypes | Adjusted | | | (cases/controls) | (cases/controls) | (cases/controls) | | GG+AG | AA | (95% CI) | TT+CT | CC | (95% CI) | 0-2 | 3 | (95% CI) |
| | Age, month | | ≤18 | 59/199 | 6/34 | 0.59 (0.24-1.47) | 0.256 | 60/198 | 5/35 | 0.47 (0.18-1.25) | 0.130 | 61/199 | 4/34 | 0.38 (0.13-1.12) | 0.079 | | >18 | 72/254 | 7/44 | 0.58 (0.25-1.34) | 0.201 | 72/254 | 7/44 | 0.58 (0.25-1.34) | 0.201 | 72/256 | 7/42 | 0.61 (0.26-1.42) | 0.253 | | Gender | | Females | 60/206 | 4/27 | 0.50 (0.17-1.49) | 0.213 | 59/206 | 5/27 | 0.64 (0.23-1.73) | 0.374 | 60/207 | 4/26 | 0.52 (0.17-1.55) | 0.240 | | Males | 71/247 | 9/51 | 0.61 (0.29-1.31) | 0.207 | 73/246 | 7/52 | 0.45 (0.20-1.04) | 0.063 | 73/248 | 7/50 | 0.48 (0.21-1.10) | 0.083 | | Clinical stages | | I+II | 48/453 | 5/78 | 0.61 (0.23-1.58) | 0.307 | 49/452 | 4/79 | 0.47 (0.16-1.33) | 0.154 | 49/455 | 4/76 | 0.48 (0.17-1.39) | 0.178 | | III+IV | 76/453 | 6/78 | 0.45 (0.19-1.07) | 0.072 | 76/452 | 6/79 | 0.44 (0.19-1.06) | 0.066 | 76/455 | 6/76 | 0.47 (0.20-1.11) | 0.084 |
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OR, odds ratio; CI, confidence interval. for age and gender, omitting the corresponding stratification factor. |
