A Robust Gene Expression Prognostic Signature for Overall Survival in High-Grade Serous Ovarian Cancer

Figure 2

Identification of genes associated with prognostic function in HGSOC. (a) The 562 consistently deregulated probe IDs identified represent 488 genes in the cancer patients. Through Kaplan–Meier survival analysis, 232 genes were found to be significantly associated with overall survival of HGSOC patients. Functional annotation was carried out for the 232 genes. (b) Examples of Kaplan–Meier survival curves for four individual genes significantly associated with overall survival in HGSOC patients, which was divided into two groups to maximize the difference in survival using log-rank testing between groups. We used HR and log-rank -value for the curve comparison between the groups.

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