Texture Analysis of Dynamic Contrast-Enhanced MRI in Evaluating Pathologic Complete Response (pCR) of Mass-Like Breast Cancer after Neoadjuvant Therapy

Table 2

Interobserver agreement for ROI drawing (Cronbach’s test).

Features	Cronbach’s alpha	95% confidence interval	F value
Post‐NAT enhancing volume	0.983	0.963, 0.992	57.30	<0.001
Interquartile range	0.965	0.927, 0.983	28.78	<0.001
Skewness	0.410	−0.240, 0.719	1.70	0.081
75 percentile	0.972	0.941, 0.987	35.40	<0.001
Uniformity	0.815	0.612, 0.912	5.41	<0.001
Median	0.938	0.870, 0.971	16.21	<0.001
Energy	0.997	0.995, 0.999	396.06	<0.001
Robust mean absolute deviation	0.969	0.935, 0.985	32.14	<0.001
Mean absolute deviation	0.972	0.940, 0.986	35.14	<0.001
Maximum	0.993	0.985, 0.997	142.62	<0.001
Root mean squared	0.959	0.913, 0.980	24.28	<0.001
90 percentile	0.982	0.961, 0.991	54.52	<0.001
Minimum	−0.140	−1.395, 0.457	0.88	0.637
Entropy	0.972	0.941, 0.987	35.57	<0.001
Range	0.989	0.976, 0.995	88.52	<0.001
Variance	0.967	0.931, 0.984	30.66	<0.001
10 percentile	0.725	0.422, 0.869	3.64	<0.001
Kurtosis	0.877	0.743, 0.942	8.16	<0.001
25 percentile	0.857	0.700, 0.932	7.01	<0.001
Mean	0.944	0.883, 0.974	18.02	<0.001

Features with Cronbach’s alpha >0.9.