Texture Analysis of Dynamic Contrast-Enhanced MRI in Evaluating Pathologic Complete Response (pCR) of Mass-Like Breast Cancer after Neoadjuvant Therapy
Table 3
Comparing features in pCR and non-pCR groups.
pCR (n = 40)
Non-pCR (n = 72)
Z/t
AUC (95% CI)
Post‐NAT enhancing volume (mm3)
176.05 (31.05, 321.05)
1704.15 (1010.78, 2397.53)
−5.799
<0.001
0.83 (0.75–0.91)
Early phase
Energy
12.18 × 106 (0.58 × 106, 25.77 × 106)
233.12 × 106 (121.26 × 106, 344.97 × 106)
−5.854
<0.001
0.84 (0.76–0.91)
Entropy
2.49 (2.11, 2.87)
4.11 (3.87, 4.35)
−5.902
<0.001
0.84 (0.76–0.92)
Mean absolute deviation
64.29 (47.58, 80.99)
126.09 (110.88, 141.31)
−5.350
<0.001
0.81 (0.72–0.90)
Robust mean absolute deviation
39.36 (25.90, 52.83)
87.41 (75.75, 99.07)
−5.322
<0.001
0.81 (0.71–0.90)
Root mean squared
267.75 (213.47, 318.03)
466.01 (417.13, 514.89)
−5.113
<0.001
0.80 (0.70–0.88)
Variance
9.79 × 103 (4.66 × 103, 14.92 × 103)
30.62 × 103 (23.73 × 103, 37.50 × 103)
−5.447
<0.001
0.81 (0.72–0.90)
rSImean
0.68 (0.56, 0.81)
0.93 (0.84, 1.02)
−3.226
0.002
0.68 (0.58–0.79)
rSImedian
0.67 (0.55, 0.79)
0.90 (0.81, 1.00)
−3.105
0.002
0.66 (0.56–0.77)
rSI75 percentile
0.82 (0.66, 0.98)
1.14 (1.03, 1.26)
−3.416
0.001
0.69 (0.59–0.80)
rSI90 percentile
0.94 (0.75, 1.13)
1.39 (1.26, 1.51)
−3.950
<0.001
0.72 (0.62–0.83)
rSImaximum
1.09 (0.86, 1.33)
1.91 (1.70, 2.13)
−4.621
<0.001
0.76 (0.67–0.86)
rSIinterquartile range
0.27 (0.19, 0.35)
0.45 (0.40, 0.51)
−4.172
<0.001
0.74 (0.64–0.84)
rSIrange
0.74 (0.54, 0.95)
1.67 (1.45, 1.90)
−5.204
<0.001
0.79 (0.71–0.88)
Delay phase
Energy
24.26 × 106 (1.18 × 106, 47.35 × 106)
305.36 × 106 (164.77 × 106, 445.95 × 106)
−5.720
<0.001
0.83 (0.75–0.91)
Entropy
2.77 (2.37, 3.18)
4.35 (4.13, 4.57)
−5.691
<0.001
0.83 (0.74–0.91)
Mean absolute deviation
86.45 (68.58, 104.32)
146.25 (130.89, 161.62)
−4.579
<0.001
0.76 (0.67–0.86)
Robust mean absolute deviation
54.05 (39.26, 68.85)
103.74 (92.29, 115.18)
−4.746
<0.001
0.77 (0.67–0.87)
Root mean squared
373.28 (304.75, 441.81)
576.74 (527.95, 625.52)
−4.755
<0.001
0.77 (0.68–0.87)
Variance
14.78 × 103 (9.05 × 103, 20.50 × 103)
38.54 × 103 (30.43 × 103, 46.65 × 103)
−4.755
<0.001
0.77 (0.68–0.87)
rSImean
0.89 (0.76, 1.03)
1.15 (1.06, 1.24)
−3.242
0.002
0.69 (0.59–0.79)
rSImedian
0.89 (0.76, 1.02)
1.15 (1.05, 1.24)
−3.254
0.002
0.68 (0.58–0.78)
rSI75 percentile
1.07 (0.91, 1.24)
1.42 (1.31, 1.53)
−3.651
<0.001
0.70 (0.60–0.80)
rSI90 percentile
1.21 (1.02, 1.41)
1.66 (1.53, 1.78)
−4.026
<0.001
0.73 (0.63–0.83)
rSImaximum
1.39 (1.15, 1.64)
2.16 (1.95, 2.36)
−4.445
<0.001
0.75 (0.66–0.85)
rSIinterquartile range
0.37 (0.28, 0.45)
0.55 (0.49, 0.61)
−3.419
0.001
0.70 (0.59–0.81)
rSIrange
0.97 (0.73, 1.20)
1.90 (1.67, 2.13)
−4.821
<0.001
0.78 (0.68–0.87)
All data are presented as mean (95% CI); value with Wilcoxon rank-sum test or independent sample t-test; AUC >0.8.
