Research Article
Are Long Noncoding RNAs New Potential Biomarkers in Gastrointestinal Stromal Tumors (GISTs)? The Role of H19 and MALAT1
Table 3
Association between clinicopathological features and lncRNA MALAT1 expression levels.
| Variable | MALAT1 expression level | Higher | Lower |
| Patients | 24 | 12 | 12 |
| Mitotic rate | <5/50 HPF: 0 | | | ≥5/50 HPF: 6 | 6 | 1 |
| Tumor size | <5 cm: 1 | 1 | | ≥5 cm: 6 | 5 | 1 |
| Tumor site | Stomach/small intestine: 9 | 5 | 4 | Colon-rectum: 2 | | 2 |
| Risk classification (Miettinen’s criteria) | Low risk/very low risk: 4 | 2 | 2 | Intermediate/high risk: 4 | 3 | 1 |
| Onset | Localized: 14 | 6 | 8 | Metastatic:10 | 5 | 5 |
| Mutational analysis | Wild-type: 4 | 1 | 3 | Mutated: 16 | | 8 |
|
|