Incorporating the Number of PLN into the AJCC Stage Could Better Predict the Survival for Patients with NSCLC: A Large Population-Based Study

Table 2

Influence of different variables on overall survival (OS) by pN stage for patients with NSCLC analyzed by Cox proportional hazard model.

Variables	Univariate analysis		Multivariate analysis
	Wald χ^2		HR (95% CI)
Age	286.45	<0.001		<0.001
< 65			Reference
≥ 65			1.578 (1.497–1.664)	<0.001
Race	18.08	<0.001		<0.001
White			Reference
Black			1.019 (0.927–1.121)	0.691
Others			0.799 (0.719–0.887)	<0.001
Sex	134.46	<0.001		<0.001
Female			Reference
Male			1.359 (1.290–1.431)	<0.001
Histology	48.72	<0.001		<0.001
Squamous			Reference
Adenocarcinoma			0.831 (0.789–0.875)	<0.001
pT stage	273.10	<0.001		<0.001
pT1			Reference
pT2			1.345 (1.267–1.429)	<0.001
pT3			1.951 (1.770–2.151)	<0.001
pT4			1.837 (1.679–2.011)	<0.001
pN stage	633.92	<0.001		<0.001
pN0			Reference
pN1			1.630 (1.534–1.733)	<0.001
pN2			2.157 (2.023–2.300)	<0.001
pN3			2.799 (1.983–3.949)	<0.001