Research Article
GASC1-Adapted Neoadjuvant Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma: A Prospective Clinical Biomarker Trial
Table 3
Univariate and multivariate analyses of risk factors for the overall survival.
| | Univariate analysis | Multivariate analysis | | Hazard ratio | 95% CI | |
| Age (year) | | | | | <65/≥65 | 0.448 | | | | Gender | | | | | Male/female | 0.679 | | | | Tumor location | | | | | Upper/middle/lower | 0.156 | | | | cT | | | | | T1/T2/T3 | 0.028 | 2.366 | 1.233–4.569 | 0.01 | cN | | | | | N0/N+ | 0.014 | | | | Pathological grade | | | | | G1/G2/G3 | 0.044 | | | | GASC1 expression | | | | | High/low | 0.039 | 1.89 | 1.011–4.216 | 0.048 |
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Log-rank test. Adjusted 95% confidence interval. Cox proportional hazard model. |