Novel Blood Indicators of Progression and Prognosis in Renal Cell Carcinoma: Red Cell Distribution Width-to-Lymphocyte Ratio and Albumin-to-Fibrinogen Ratio

Table 2

Associations of RLR and AFR with clinicopathological characteristics.

Characteristic	RLR			AFR
	<8.6 (n = 185)	≥8.6 (n = 88)		<9 (n = 83)	≥9 (n = 190)
Age, (years)	50.83 ± 13.08	56.09 ± 12.25	0.002	56.19 ± 12.07	50.92 ± 13.14	0.020
Gender			0.597			0.009
Male	136	62		129	69
Female	49	26		61	14
BMI, (kg/m^2)	24.32 ± 4.63	22.07 ± 3.25	<0.001	23.34 ± 4.18	23.71 ± 4.44	0.527
HGB, (g/L)	133.98 ± 17.04	119.87 ± 20.89	<0.001	121.53 ± 23.25	132.88 ± 16.51	<0.001
Ca, (mmol/L)	2.30 ± 0.10	2.29 ± 0.22	0.640	2.30 ± 0.20	2.30 ± 0.13	0.776
Creatinine, (umoI/L)	84.50 ± 26.21	84.64 ± 25.29	0.968	92.57 ± 32.11	81.04 ± 21.80	0.003
Ccr, (ml/min)	89.97 ± 24.58	81.02 ± 17.55	0.001	77.73 ± 20.50	91.17 ± 22.76	<0.001
Basic disease			0.008			0.300
No	144	55		57	142
Yes	41	33		26	48
Symptom			0.013			0.001
No	99	33		28	104
Yes	86	55		55	86
Surgery			0.156			0.006
Endoscopic	143	61		53	154
Open	42	27		30	39
Site			0.737			0.597
Left	99	49		47	101
Right	86	39		36	89
Tumour size (D/cm)	4.50 (3.45 – 3.05)	5.90 (3.50 – 9.00)	0.010	7.00 (4.00 – 9.50)	4.10 (3.00 – 6.00)	<0.001
Tumour necrosis			0.482			0.186
Absent	103	45		50	98
Present	82	43		33	92
Tumour type			0.044			0.034
ccRCC	145	59		55	149
nccRCC	40	29		28	41
TNM stage			0.027			<0.001
I	130	50		33	147
II	33	15		19	29
III	13	15		19	9
IV	9	8		12	5
Fuhrman grade			0.121			0.001
G1 + G2	117	47		38	126
G3 + G4	68	41		45	64