Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify SOX13 to Be Involved in Invasion and Progression of Pancreatic Cancer

Figure 3

The biological function of let-7c in the progression and invasion was investigated by transiently inducing (a) let-7c into Panc-1 cell line; (b) restoration of miRNA let-7c in Panc-1 cells significantly reduced proliferation; and (c) invasion and (d) colony formation efficiency compared with pre-miR control.

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