Rab11a Is Overexpressed in Gastric Cancer and Regulates FAK/AKT Signaling

Figure 6

Rab11a regulates MMP2, cyclin D1, Bcl-2, p-FAK, and p-AKT. Western blot showed that Rab11a overexpression upregulated the protein expression of MMP2, cyclin D1, and Bcl-2. Rab11a also increased phosphorylation of FAK and AKT. Rab11a siRNA showed the opposite effects on these proteins. Quantification of western blot that was performed was indicated.

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