Research Article
Meningiomas: An Overview of the Landscape of Copy Number Alterations in Samples from an Admixed Population
Table 5
Some genes found in the most frequent altered cytobands in the analyzed meningioma samples correlating the histological grade.
| Cytobands | Genes | Histological grade | Type of CNA | Frequency in the samples (%) |
| 1p35.3 | THEMIS2 | I, II, III | Loss | 76 | RPA2 | | | | SESN2 | | | | RCC1 | | | | 3q29 | PAK2 | I, III | Loss | 54 | 4p14 | RFC1 | I, III | Loss | 57 | 8p22 | MSR1 | I | Gain | 64 | 11q23.3 | CXCR5 | I, III | Loss | 51 | 14q13.1-q13.2 | EAPP | I, II, III | Loss | 67 | 14q32.33 | FAM30A | I, II, III | Gain | 100 | 15q15.1 | CHAC1 | I, II, III | Loss | 57 | 16q21 | CDH11 | I, II | Gain | 51 | 16q22.1 | SF3B3 | I, III | Loss | 54 | 17q21.33 | COL1A1 | I, II | Gain | 67 | 22q13.1-q13.2 | ST13 | I, II, III | Loss | 82 | TOB2 | | | |
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Consider loss/deletion and gain/amplification. |