Association of Genetic Polymorphisms in TNFRSF11 with the Progression of Genetic Susceptibility to Gastric Cancer

Table 7

Stratified analyses between rs9533156 polymorphism and risk by sex, age, smoking status, and alcohol consumption.

Variable	(Case/control)			Adjusted OR (95% CI);			(TC + CC) VSTT	CCVS (TT + TC)
	TT	TC	CC	TT	TC	CC
Sex
Male	91/129	206/210	84/95	1.00	1.39 (1.00–1.93); : 0.050	1.25 (0.84–1.87); : 0.265	0.93 (0.67–1.30); : 0.671	1.01 (0.72–1.41); : 0.957
Female	48/63	90/100	39/49	1.00	1.18 (0.74–1.89); : 0.488	1.05 (0.59–1.84); : 0.879	1.14 (0.73–1.77); : 0.572	0.94 (0.58–1.52); : 0.800
Age
<62	79/89	118/143	61/69	1.00	0.93 (0.63–1.37); : 0.713	0.99 (0.63–1.58); : 0.986	0.95 (0.66–1.37); : 0.787	1.00 (0.68–1.48); : 0.997
≥62	60/103	178/167	62/75	1.00	1.83 (1.25–2.68); : 0.002	1.42 (0.89–2.26); : 0.138	1.70 (1.18–2.45); : 0.004	0.94 (0.64–1.37); : 0.740
Smoking status
Never	87/146	201/227	80/96	1.00	1.49 (1.07–2.06); : 0.017	1.40 (0.94–2.08); :0.098	1.46 (1.07–1.99); : 0.016	1.08 (0.77–1.51); : 0.654
Ever	52/46	95/83	43/48	1.00	1.01 (0.62–1.66); : 0.961	0.80 (0.45–1.40); : 0.425	0.93 (0.59–1.48); : 0.765	0.79 (0.49–1.26); : 0.320
Alcohol consumption
Never	109/153	235/241	96/101	1.00	1.37 (1.01–1.86); : 0.043	1.33 (0.92–1.94); : 0.128	1.36 (1.02–1.81); : 0.037	1.09 (0.80–1.50); : 0.584
Ever	30/39	61/69	27/43	1.00	1.15 (0.64–2.07); : 0.642	0.82 (0.42–1.61); : 0.556	1.02 (0.59–1.77); : 0.940	0.75 (0.43–1.30); : 0.299